a lowly engineer 's attempt at hard science reporting and digressions into a childhood ecstacy not yet lost
Sunday, August 03, 2014
Antibiotic resistant bacteria, and why I stockpile but do not use
This is a year old piece about an AB resistant bacterial strain. Oddly, it is referred to as an opinion piece.There are more current reports that simply verify and expand the findings a bit.Here in tick-vector-illness-central the medical community had to be dragged kicking and screaming to write scripts for agents effective against Lyme and other bacteria transmitted via tick bites. This has proven to be very unwise. Now, all tick bites are treated with a one day course of doxycycline as prophylaxis. If a person goes on to present with Lyme--or other bacterial illness--the standard course is a 21 day treatment.This CRE issue is evolution in overdrive. The selective pressure being resistance to common and uncommon antibiotics.This is why I have ABX on hand, but have never given myself a course of any antibiotic. In my 53 years of life, I have been on two courses of ABX. The first was back in 1980 when I was given erythromycin for a non-specific urinary tract infection(yes, I know how disturbing that reads), and the last was doxycycline to treat Lyme. I am very cautious about laissez-faire use of ABX. If only the bovine and chicken husbandry industries would follow suit. Don't expect change anytime soon. These are powerful industries, and 'Mericans want their cheap animal products. It is a matter of 'having choices' after all. No one dare do anything that is scientifically sound if it interferes with individual choices. *huge eyeroll*It is likely the case in other New World countries with the possible exception of Canada.If highly therapy resistant bacterial strains become the norm, then going to a hospital could be a dangerous thing to do.One needs to be cognizant that evolution does not work on time scales, but generational scales. Fast growing bacteria can multiply in as little as 20 minutes. Let us perform a worst case thought experiment for humankind, and a best case scenario for out bacterial foes.Let us use 1948 as a starting point. Penicillin was--by then--widely available and used. The possible doublings--and hence chances for errors in replication which could lead to resistance--is roughly 174,155,117 generations. The entire genome of a fast growing bacterial species could be replaced several times over given the geometric progression under ideal circumstances. That is really quite sobering.Some researchers are predicting a 'post-antibiotic' future. Almost surely some microbes will defeat current medicine while others will not.Even now, lack of exposures is by far the best weapon. Sure bacteria are ubiquitous, but thankfully, most are not pathogenic to humans.Hand washing beats hand wringing every time.Be informed, but don't succumb to irrational fears. Yes, I know how odd that may seem coming from me, but I do not fear pathogens--in fact, I rarely fear things which might ACTUALLY kill me--but I do believe in being prepared.I am fully aware of my awfully clipped sentence structure that pervades this post. This post is also lacking proper linkages and segues between topics. I am simply too fatigued to care. It has been a hell of a weekend, and my brain is full. I would like to be excused now. I have the Sword of Damocles still over my head. It is not yet known if and what manner my eye issues are going to take. I have a mere eight days to get my ocular pressures into an acceptable area. One eye is really close, the other not nearly so. I'm coming to terms with the whole mess, but it still troubles.
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