a lowly engineer 's attempt at hard science reporting and digressions into a childhood ecstacy not yet lost
Thursday, July 31, 2014
Life'll Kill Ya.*
*(Apologies to Warren Zevon..I was fortunate to talk to The Excitable Boy after a concert he played in Concord, NH.)Okay gentle reader, I am not going to wade into the deep end of the pool today, for danger lurks in the warm shallows, and that is where our story comes from today.Bacteria rarely get their due. Flesh eating bacteria, now that is news! I am not excited over necrotizing bacteria lurking in warm, shallow brackish and/or salt water.However, here is another case where the broad spectrum antibiotic doxycycline(combined with a second AB is a first line treatment)I recently finished a 21 day course of doxycycline for Lyme(Borreliosis). I would never advocate prophylactic use of ANY drug. However, given that I am sometimes away from the realistic possibility of proper medical treatment I think it prudent to have two different agents on hand before wandering way off the grid. My insurance paid a princely sum for my course of doxycycline. There are simple ways to obtain a good broad spectrum topical AB--say chlorhexidine hyclate, for instance--and easy ways to obtain doxycycline and perhaps ampicillin and/or amoxycillin WITH clavulanic acid to increase potency against treatment resistant bacterial strains.Of course these things would be the last things to add to your 'end of the world' first-aid kit.I asked my favorite pharmacist about different combinations of meds for going way off the grid, and she said that these might all prove useful.The reason for two--or even three--broad spectrum antibiotics(ABX) is due to modes of action. If you do not know why this is an important consideration, you should not search out any ABX. Honestly. Although these particular ABX are chosen for wide effectiveness against both gram-positive and gram-negative bacteria, without knowing modes of action--and the various types of microbial targets--you are likely to do the wrong thing.There is no way that I would ever attempt to procure anti-virals. The only AV class that I am even remotely familiar with are acyclovir and its derivatives. Palliative care and POSSIBLE prophylactic use of ABX are the limit of my knowledgebase concerning how to treat viral conditions in the middle of nowhere.This post does not specify what to use for any bacterial or parasitic infection. You have to do your own research on what you are likely to confront in your area of the wild world. I am most likely a lot less ready than I think I am. Let us hope that I will never have to put any of my remedial first-aid skills to the test...again. I did save a fellow that concussed himself while riding a motocrosser way off the track. That was an easy one. Happy Thursday all! Be safe, and be prepared!On edit: The reasons for this odd post can be found here, where I blather on about vector-borne illness, here, where I get downright evangelical about vector illnesses, and finally here, where I was tick bitten, but Lyme(borreliosis) had not yet been confirmed. All of those things comprise the impetus for today's ramble. Sorry to put you through that again.
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